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AVN-944 (C005B-308987)

Catalog No.
C005B-308987
Mfr. No.
SML3440-5MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
EA
Price: $190.56
List Price: $211.73

Biochem/physiol Actions AVN-944 is an orally bioavailable, highly selective, nonnucleoside and uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with antitumor and antiviral activities. AVN-944 depletes intracellular GMP levels

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Biochem/physiol Actions

AVN-944 is an orally bioavailable, highly selective, nonnucleoside and uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with antitumor and antiviral activities. AVN-944 depletes intracellular GMP levels and inhibits DNA and RNA viruses replication via reduction of GTP pools in infected cells. Arrests a wide range of hematologic and epithelial tumor cell types proliferation (IC50 of 0.02 µM to 0.279 µM).

UPC:
51111870
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
SML3440-5MG
CAS:
297730-17-7

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