Bafilomycin A1 (C007B-028845)

Bafilomycin A1 is a potent and selective inhibitor of V-ATPase (vacuolar-type (v-type) H+ ATPase) and belongs to a class of membrane ATPase inhibitors. The compound can inhibit E1E2 ATPases from sarcoplasmic reticulum, Escherichia coli, and ox brain versus F1F0 ATPases found in bacteria and mitochondria. Some of the more bafilomycin A1 affected ATPases include Neurospora and plant vacuoles, as well as chromaffin granules. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Research shows that Bafilomycin A1 can inhibit macroautophagy and promote apoptosis in colon cancer cells.A macrolide antibiotic and potent and selective inhibitor of vacuolar-type (v-type) H+ ATPase. Specification: ≥95.0 % MDL Number: MFCD06795130 Molecular Formula: C35H58O9 Molecular Weight: 622.83 PubChem CID: 6436223 Isomeric SMILES: C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C Beilstein Registry Number: 4730700 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B101389-SCI_bfd4de3a4107ae40aba59901ddb52dcf.pdf

UPC:

51111733

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

B101389-1mg

CAS:

88899-55-2

Product Size:

1mg

Hazard Statement Codes:

H315:H319:H335

Precautionary Statement Codes:

P261:P264:P271:P280:P302+P352:P304+P340:P305+P351+P338:P362+P364:P405:P403+P233:P501