Belvarafenib TFA

Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.Appearance:SolidIC50& Target:IC50: 56 nM(B-RAF), 7 nM(B-RAFv 600E ), 5 nM(C-RAF) .In Vitro:Belvarafenib (Example 116) is a potent and pan RAF inhibitor with antineoplastic activity. The IC 50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively. It also shows high inhibitory activity for FMS, DDR1 and DDBiological Activity:Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively. Specification: ≥99% Molecular Formula: C25H17ClF4N6O3S Molecular Weight: 592.95

UPC:

51112019

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

B659018-5mg

Product Size:

5mg