Calcium Signaling Agents

A cell-permeable inhibitor of caspase-1 (ICE Interleukin-1&#946 Converting Enzyme), caspase-4, and caspase-5. The C-terminal YVAD-CHO sequence of this peptide is a highly specific, potent, and reversible inhibitor of caspase-1 (K i = 1 nM).

A cell-permeable and irreversible inhibitor of caspase-1 (K i = 760 pM), caspase-4, and caspase-5. Inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation.

A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1) An irreversible inhibitor of caspase-2 (ICH-1). Biochem/physiol Actions Cell permeable: yes Primary Target caspase-2 Product does not compete with ATP.

A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1) An irreversible inhibitor of caspase-2 (ICH-1). Biochem/physiol Actions Cell permeable: yes Primary Target caspase-2 Product does not compete with ATP.

A potent, cell-permeable and irreversible inhibitor of CPP-32/apopain, a member of the ICE/CED-3 family of cysteine proteases. A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and

A potent, cell-permeable and irreversible inhibitor of CPP-32/apopain, a member of the ICE/CED-3 family of cysteine proteases. A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and

A potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases. A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10.

A potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases. A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10.

A tetrapeptidyl aldehyde that acts as a potent, reversible and active site binding inhibitor of caspases-3 and -7 (IC 50 = 3.2 nM and 22.

A reversible caspase-4 (ICH-2) inhibitor. A reversible caspase-4 inhibitor.

A potent, cell-permeable, and reversible inhibitor of caspase-6.The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.

A potent, cell-permeable, and reversible inhibitor of caspase-8 and Granzyme B. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability