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Sigma-Aldrich

BRASSININ (C005B-311829)

Biochem/physiol Actions Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. In lung cancer cells, brassinin inhibits constitutive and

Description

Biochem/physiol Actions

Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3. It appears that brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling.

Other Notes

air sensitive

Specifications
UPC:
51111652
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
5
Unit of Measurement:
MG
MPN:
SML1635-5MG
CAS:
105748-59-2
Catalog No. C005B-311829
Price: $208.87
List Price: $232.07
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