Aladdin Scientific
BRD7586 (C007B-336364)
BRD7586 is a cell-permeable small-molecule inhibitor of SpCas9. BRD7586 is the smallest known anti-CRISPR.In VitroBRD7586 specifically engages SpCas9 but not Cas12a in cells. BRD7586 (0-20 μM: 24 h) dose-dependently inhibits SpCas9 in the
Description
BRD7586 is a cell-permeable small-molecule inhibitor of SpCas9. BRD7586 is the smallest known anti-CRISPR.In VitroBRD7586 specifically engages SpCas9 but not Cas12a in cells. BRD7586 (0-20 μM; 24 h) dose-dependently inhibits SpCas9 in the HiBiT-knock-in assay in HEK293T cells. BRD7586 (20 μM; 48 h) enhances the ratio of on-target versus off-target in HEK293T cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid. Specification: 0.99 Molecular Formula: C17H14ClN3O3S2 Molecular Weight: 407.89
Specifications
- UPC:
- 51202302
- Condition:
- New
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- B650447-50mg
- CAS:
- 895460-70-5
- Product Size:
- 50mg
Catalog No.
C007B-336364
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