BRETTPHOS PD G1 METHYL T-BUTYL ETHER ADDUCT MAY CONTAIN UP TO 1 MOLE EQUIVALENT OF MTBE 97% (C005B-232527)

General description

BrettPhos Pd G1 is a Buchwald first generation (G1) palladacycle precatalyst that can be used in cross-coupling reactions for the formation of C-C, C€“N, C€“O, C€“F, C€“CF3, and C€“S bonds. The formation of the active Pd(0) species in the G1 precatalyst is easy to generate, requiring merely a deprotonation with a base. The resulting catalyst is very active, even at temperatures down to −40 °C, and can be used in a variety of cross-coupling protocols.

Application

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Catalyst for:

• C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and secondary amines
• Amination reaction
• N-arylation of aminophenols

Molecular Weight: 798.81. Empirical Formula: C₄₃H₆₃ClNO₂PPd. Quality Level: 100. Assay: 97%. form: solid. feature: generation 1. reaction suitability: core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings. mp: 198-204 . °C. functional group: phosphine. SMILES string: COC(C)(C)C.NCCc1ccccc1[Pd]Cl.COc2ccc(OC)c(c2P(C3CCCCC3)C4CCCCC4)-c5c(cc(cc5C(C)C)C(C)C)C(C)C. InChI: 1S/C35H53O2P.C8H10N.C5H12O.ClH.Pd/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28. 9-7-6-8-4-2-1-3-5-8. 1-5(2,3)6-4. . /h19-25,27-28H,9-18H2,1-8H3. 1-4H,6-7,9H2. 1-4H3. 1H. /q. . . . +1/p-1. InChI key: OWHWOTGYDWMPCA-UHFFFAOYSA-M. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

UPC:

51372500

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

GR

MPN:

718750-1G