BS-181-5 mg

BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC₅₀ value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7. BS-181 has been shown to inhibit the phosphorylation of Cdk7 substrates, to promote cell cycle arrest and apoptosis, to inhibit the growth of cancer cell lines in vitro, and to inhibit the growth of MCF-7 human xenografts in nude mice.

Shipping Information:

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UPC:

51111756

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No"

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

17996-5

Model Number:

C815D45

Temperature Control Device:

Yes