γ-Butyrolactone

γ-Butyrolactone (GBL) is a related lactone analog of γ-hydroxybutyric acid (GHB), a widespread drug of abuse, identified as an endogenous constituent of the mammalian brain, in which it exhibits a strong central nervous system depressant effect. GBL is considered as a legal substitute of GHB, and commonly identified in beverages including coffee, apple cider vinegar, tea, carbonated drinks, etc. Application γ-Butyrolactone may be used as an analytical reference standard for the quantification of the analyte in roasted Italian chestnuts, wine samples, beverages using chromatography techniques. Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Biochem/physiol Actions Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release. Precursor of γ-hydroxybutyric acid (GHB); blocks dopamine release.

UPC:

12142207

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

ML

WeightUOM:

LB

MPN:

90970

CAS Number:

96-48-0