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Aladdin Scientific

C-170 (C007B-105550)

C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.In vitro activity:In THP-1 cells, pretreated with STING-IN-2

Description
C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.In vitro activity:In THP-1 cells, pretreated with STING-IN-2 (C-170;?0.5 μM) and stimulated with cGAMP.?STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels. Specification: 10mM in DMSO Molecular Formula: C15H16N2O4 Molecular Weight: 288.3 PubChem CID: 2059265 Isomeric SMILES: CCCCC1=CC=C(C=C1)NC(=O)C2=CC=C(O2)[N+](=O)[O-]
Specifications
UPC:
41115715
Condition:
New
Weight:
10.93 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
C580322-1ml
CAS:
346691-38-1
Product Size:
1ml
Catalog No. C007B-105550
Price: $237.81
List Price: $264.24
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