C4D (POLYCLONAL) 7ML PREDILUTE (C005B-227724)

General description

Acute humoral rejection is mediated by antibodies to the donor endothelium that activates the classical complement pathway. This leads to a number of split products of complement proteins. C4d is a fragment of C4 complement released during activation of the classic complement pathway by the antigen-antibody complex. C4d deposits in peritubular capillaries and is regarded as an indirect sign of an antibody response. C4d can be a useful tool for indicating acute renal allograft rejection.

Quality

IVD

IVD

IVD

RUO

Linkage

C4d Positive Control Slides, Product No. 404S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

biological source: rabbit. Quality Level: 100, 500. conjugate: unconjugated. antibody form: culture supernatant. antibody product type: primary antibodies. clone: SP91, monoclonal. description: For In Vitro Diagnostic Use in Select Regions (See Chart). form: buffered aqueous solution. species reactivity: human. packaging: vial of 0.1 . mL concentrate (404R-14), vial of 0.5 . mL concentrate (404R-15), bottle of 1.0 . mL predilute (404R-17), vial of 1.0 . mL concentrate (404R-16), bottle of 7.0 . mL predilute (404R-18). manufacturer/tradename: Cell Marque^™. . technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200. isotype: IgG. control: lymph node, tonsil. shipped in: wet ice. storage temp.: 2-8°C. visualization: cytoplasmic, membranous. Gene Information: human ... C4B(721). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

UPC:

41181519

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

25

Unit of Measurement:

ML

MPN:

404R-10