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Sigma-Aldrich

CARVEDILOL (C005B-059061)

Application Carvedilol has been used: as a β blocker to determine its effect on hypoxia inducible factor (HIF)-mediated erythropoiesis under hypoxia in vivo as a βAR antagonist for inhibition of bARs as a β-blocker to examine airway

Description

Application

Carvedilol has been used:

  • as a β blocker to determine its effect on hypoxia inducible factor (HIF)-mediated erythropoiesis under hypoxia in vivo
  • as a βAR antagonist for inhibition of bARs
  • as a β-blocker to examine airway mechanics in fungus-challenged mice

Biochem/physiol Actions

Cavedilol is a non-selective β-adrenergic blocker with α1 blocking activity. Carvedilol is used specifically for the treatment of heart failure and high blood pressure. It has been shown to improve left ventricular ejection fraction and may reduce mortality.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Specifications
UPC:
51262002
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
250
Unit of Measurement:
MG
MPN:
C3993-250MG
CAS:
72956-09-3
Catalog No. C005B-059061
Price: $890.64
List Price: $989.60
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