CCR6 inhibitor 1 (C007B-343276)

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancerIn VitroCCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Moneky CCR6 0.45 nM (IC 50 ) Human CCR6 6 nM (IC 50 ) Human CCR7 9400 nM (IC 50 ). Specification: 0.99 Molecular Formula: C24H23F3N4O3S Molecular Weight: 504.52

UPC:

51111731

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C650442-10mg

CAS:

2437547-04-9

Product Size:

10mg