Aladdin Scientific
CCT129957 (C007B-343864)
CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC 50 of ~3 μM and a GC 50 of 15 μM. CCT129957 inhibits Ca 2+ release in squamous carcinoma cells at ~15 μMIn VitroThe phenyl group on the left side sat in a
Description
CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC 50 of ~3 μM and a GC 50 of 15 μM. CCT129957 inhibits Ca 2+ release in squamous carcinoma cells at ~15 μMIn VitroThe phenyl group on the left side sat in a lipophilic pocket formed of various amino acids. The predicted binding mode of CCT129957 displays a robust hydrogen bond pattern as well as a lipophilic contact. CCT129957 inhibits the cell growth of renal UO-31 and the breast T-47D cancer cell lines by ~60-70%. MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:IC50: ~3 μM (Phospholipase C-γ (PLC-γ)). Specification: 10mM in DMSO Molecular Formula: C17H15N3O3 Molecular Weight: 309.32
Specifications
- UPC:
- 51111611
- Condition:
- New
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- C656824-1ml
- CAS:
- 883098-58-6
- Product Size:
- 1ml
Catalog No.
C007B-343864
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