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Sigma-Aldrich

CCT137690

Biochem/physiol Actions CCT137690 is a very potent, orally bioavailble, pan aurora kinase inhbitor (IC 50 = 15, 25, and 19 nM for Aurora A, B and C respectively). CCT137690 inhibits tumor growth in amouse xenograft model and causes multipolar

Description

Biochem/physiol Actions

CCT137690 is a very potent, orally bioavailble, pan aurora kinase inhbitor (IC50 = 15, 25, and 19 nM for Aurora A, B and C respectively). CCT137690 inhibits tumor growth in amouse xenograft model and causes multipolar spindle formation, chromosome misalignment, polyploidy and apoptosis in tumor cell lines.

Specifications
UPC:
51131738
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
5
Unit of Measurement:
MG
MPN:
SML1237-5MG
CAS:
1095382-05-0
Catalog No. C005B-312377
Price: $323.86
List Price: $359.84
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