CDK8-IN-1 (C007B-343033)

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC 50 of 3 nM.In VivoCDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The t max is 0.25 h by PO. The mean values of C max are 9940 μg/L, 12740 μg/L by IV and PO respectively. The values of AUC are 9378, 25952 by IV and PO respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CDK8 3 nM (IC 50 ). Specification: 0.99 Molecular Formula: C11H8F3N3O Molecular Weight: 255.2 PubChem CID: 86274989 Isomeric SMILES: C1=CN=CC=C1C2=CNC(=C2C(F)(F)F)C(=O)N

UPC:

51203900

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C649452-10mg

CAS:

1629633-48-2

Product Size:

10mg