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Aladdin Scientific

Cediranib (C007B-081110)

Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <:1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >:1000-fold selective more for VEGFR than PDGFR-α, CSF-1R

Description
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3, Phase 3. Specification: ≥98% Molecular Formula: C25H27FN4O3 Molecular Weight: 450.52 PubChem CID: 9933475 Isomeric SMILES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C125911-SCI_4e89510b05b613869f01babaf8b54e3b.pdf
Specifications
UPC:
51321816
Condition:
New
Weight:
0.96 Ounces
HazmatClass:
Yes
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
C125911-10mg
CAS:
288383-20-0
Health Hazards:
Toxic
Product Size:
10mg
Hazard Statement Codes:
H301:H312
Precautionary Statement Codes:
P260:P264:P270:P273:P280:P330:P391:P302+P352:P362+P364:P405:P501
Catalog No. C007B-081110
Price: $143.48
List Price: $159.42
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