Eukaryotic Cells

Biochem/physiol Actions Cellular responses to BMP-4 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF A by

BMP are members of the TGF-&#946 superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF-&#946 family proteins, BMPs are highly conserved across animal species.

BMP are members of the TGF-&#946 superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF-&#946 family proteins, BMPs are highly conserved across animal species.

Biochem/physiol Actions Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

Cell Line Origin Mouse hepatoma Cell Line Description A mouse hepatoma isolated from the BW7756 transplantable hepatoma carried in C57 leaden/J mice (see reference: Differentiation). Will synthesise in appreciable amounts only hepatic proteins that

Cell Line Origin Rat hepatoma [HGPRT-] Cell Line Description Full name Faof1C2 is a dedifferentiated variant of Fao. These cells continue to express tyrosine aminotransferase, but the liver-specific markers are mostly absent.

Cell Line Origin Mouse C3H embryo Cell Line Description Derived by exposing C3H/10T1/2 clone 8 cells with 3-methylcholanthrene for 24 hours. Subsequently they lost the property of contact inhibition.

Cell Line Origin Mouse C57BL/6J melanoma epithelial Cell Line Description Spontaneous tumour of C57 black/6J mouse originally obtained from Dr Parrish of Australian National University, Canberra. Rendered HGPRT- by selection in 20&#956g/ml

Cell Line Origin Hamster Chinese ovary Cell Line Description A subclone of the parental CHO cell line originated by Puck in 1957. The cells have an absolute requirement for L-proline.

Cell Line Origin Hamster Chinese ovary Cell Line Description A subclone of the parental CHO cell line, which was derived from the ovary of an adult Chinese hamster. Cells require proline due to the absence of the gene for proline synthesis, the

CHOZN cell lines were created utilizing Sigma&#8242s proprietary CompoZr Zinc Finger Nuclease (ZFN) technology to create genetic modifications in parental CHO-K1 cells. Cells are banked in chemically defined, animal component free EX-CELL CD CHO

Cell Line Origin Human x mouse hybrid Cell Line Description This cell line may contain a sub-chromosomal fragment of human chromosome 17 containing markers thought at the time to flank the cystic fibrosis gene. The DNA was donated from the human