Antibody Labeling and Modification Kits

CD27, a member of the nerve growth factor receptor (NGFR) superfamily, is a type I transmembrane protein consisting of a disulphide-linked 120 kDa homodimer (Bigler, 1988 Sugita, 1992 Morimoto, 1995). CD27 is expressed on mature thymocytes and on

Human TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCR alpha beta or TCR gamma delta heterodimer and the associated CD3 complex.

CD33 is a member of the siglec family (sialic acid binding immunoglobulin-like lectins) referred to as Siglec-3 (Freeman SD, Kelm S, Barber EK and Crocker PR, 1995, Blood, 2005-2012). It is the smallest member of the siglec family having a

CD38 is a 45 kDa type II integral membrane glycoprotein consisting of an N-terminal 20 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 257 amino acid extracellular domain. CD38 is associated with different molecules in

CD41 is the &#945-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa &#945 chain and a 23 kDa &#946 chain.

CD42b is a 145 kDa protein, which together with CD42c forma a 160 kDa heterodimer composed of an alpha-chain and a beta-chain, respectively. The subunits are linked together by a disulphide bond.

CD43 is a human heavily 0-glycosylated transmembrane protein, which is expressed by T cells and myeloid lineage cells (Borche, 1987 Stross, 1989). Reactivity with plasma cells has been observed (Beschomer, 1999).

CD5 is a transmembrane glycoprotein monomer with an Mr of 67,000. It possesses a large cytoplasmic domain suitable for signal transduction (Lozano, 1997).

The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family.

CD56 is a membrane glycoprotein which has multiple isoforms generated by alternative splicing from a single gene located on chromosome 11 (Costa, 1997). The core polypeptide is the 140 kDa isoform which can be variably glycosylated to produce

Antibodies against CD66 recognize the carcinoembryonic antigen (CEA) family of proteins and may be further characterized by reactivity with one or more family members indicated by a low letter after CD66: e.g.

The CD7 antigen is a membrane-bound 40 kDa glycoprotein expressed on thymocytes, mature T cells, a large majority of natural killer cells, pluripotent hematopoietic stem cells, and progenitor cells of lymphoid and myeloid cells (Bowen, 1997 &amp