Complement

Biochem/physiol Actions The complement system is a complex cascade involving proteolytic cleavage of serum glycoproteins often activated by cell receptors. This cascade ultimately results in induction of the inflammatory response, phagocyte

Application Complement C8 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). A deficiency of C8 may result in an increased susceptibility to Neisseria meningitidis.

Application Complement C8 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). In the (MAC), C8 initiates and coordinates MAC pore formation.

Native, human C8 complement component. Glycoprotein composed of three non-identical subunits of M.

Application Complement C9 from human serum is an essential part of the terminal complement system. It has been a topic in cancer research, where extracellular phosphorylation by ecto-PK of K562 cells on serine residues may serve as a protective

Native, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 &#181g/ml.

Human serum depleted of complement component C9 by affinity chromatography. Human serum depleted of complement component C9 by affinity chromatography.

Application Complement factor D is a serine protease essential for the activation of the alternative pathway in the complement system. Research of complement factor D has revealed that a self inhibitory loop is responsible for switch from a resting

Complement, Rabbit Serum is a native, rabbit serum complement. Tested for suitability for HLA-ABC serology.

Native, human iC3b complement component. iC3b is formed by the cleavage of C3b by Factor I in the presence of Factor H, CR1, or membrane cofactor protein.

The complement serum standard human is suitable for the determination of CH50 and AP50 complement activities. This allows for a test of the complement activity on the capacity of the serum to lyse red blood cells in vitro and can be used in

Complement, Guinea pig serum is suitable for evaluating the functional activity of human complement components and for other research requiring a high level of hemolytic activity. Application Complement, Guinea pig serum has been used: as a