Sigma-Aldrich
CHLOROMETHYL PIVALATE 97% (C005B-023341)
Chloromethyl pivalate reacts with sodium salt of sulbactam to yield sulbactam pivoxil . It undergoes acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine (PMEA) to yield bis (pivaloyloxymethyl) PMEA .
Description
General description
Chloromethyl pivalate reacts with sodium salt of sulbactam to yield sulbactam pivoxil. It undergoes acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine (PMEA) to yield bis(pivaloyloxymethyl) PMEA.
Application
Chloromethyl pivalate was used in the synthesis of pivaloyloxy methyl ester of ofloxacin as prodrug. It was used as the reagent during the synthesis of an isoindoline-annulated, tricyclic sultam library via microwave-assisted, continuous-flow organic synthesis.
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Specifications
- UPC:
- 51284127
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- Quantity:
- 25
- Unit of Measurement:
- GR
- MPN:
- 141186-25G
- CAS:
- 18997-19-8
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