CHO-K1/ADRA1A Stable Cell Line,2vials

The a1-adrenergic receptor (AR) family consists of three closely related gene products (a_1A, a_1B, and a_1D) that mediate the actions of norepinephrine (NE) and epinephrine in sympathetically innervated tissues and brain. a1-ARs belong to the G protein-coupled receptor family and consist of single polypeptide chains predicted to have seven transmembrane spanning domains. With similar pharmacological and signaling properties, a1-AR subtypes act through Gq/11 proteins to activate phospholipase C, increase both inositol 1,4,5-trisphosphate production and intracellular Ca 2+ . Once activated by binding, a1-ARs initiate the cellular pathways leading to the regulation of physiological effects, including blood pressure maintenance, glucose metabolism, renal sodium reabsorption, and cardiac inotropy.

UPC:

51262101

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

M00225

Controlled Substances and Cyanide:

Yes