Cholin salicylate (C008B-267013)

Salicylate choline is a derivative of Aspirin (acetylsalicylic acid). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer.

Specifications & Purity: Salicylate choline is a derivative of Aspirin (acetylsalicylic acid). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer.

Grade: Moligand™

Molecular Formula: C12H19NO4

Molecular Weight: 241.28

EC Number: 217-948-8

PubChem CID: 54686350

Isomeric SMILES: C[N+](C)(C)CCO.C1=CC=C(C(=C1)C(=O)O)[O-]

Storage Temperature: Store at 2-8°C

Shipped in: Wet ice

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C342731-SCI_6d722978df42d485562888b2920e6c08.pdf

UPC:

51132243

Weight:

1.23 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C342731-5g

Country of Origin:

China

CAS:

2016-36-6

Product Size:

5g

Harmonized Tariff Code:

2918.23.50

Hazard Statement Codes:

H302;H315;H319

Precautionary Statement Codes:

P264;P270;P280;P321;P330;P302+P352;P305+P351+P338;P362+P364;P501;P264+P265;P301+P317;P337+P317;P332+P317