Chrysosplenetin (C008B-269153)

Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3AForm:SolidIC50& Target:CYP3 CYP3A

Flavonoids Flavonols Phenols Polyphenols

Specifications & Purity: Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3AForm:SolidIC50& Target:CYP3 CYP3A

Grade: Moligand™

Molecular Formula: C19H18O8

Molecular Weight: 374.34

PubChem CID: 5281608

Isomeric SMILES: COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O

Storage Temperature: Store at 2-8°C;Protected from light;Argon charged;Desiccated

Shipped in: Wet ice

UPC:

51302305

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C650116-25mg

Country of Origin:

China

CAS:

603-56-5

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90