Collagenase NB 1 From Clostridium Histolyticum (C007B-096569)

DescriptionThis highly purified collagenase quality is used for isolation of sensitive cells and guarantees high yields and viability. In combination with Neutral Protease NB Collagenase NB is especially applicable to isolation of pancreatic islets of Langerhans.Collagenase NB is recommended for applications which have to meet requirements like tissue engineering and transplantation into humans.SpecificationsContains chromatographically highly purified class I and class II collagenase (1).Largely free from clostripain, trypsin-like protease and neutral protease.Vial contains not less than 2000 PZ U collagenase.PZ activity (Wnsch): 3.000 U/mgEndotoxin ‰¤ 10.0 EU**/mg (Ph. Eur.)Microbiological examination: Total aerobic microbial count (TAMC), total combined yeast/moulds count (TYMC), absence of Clostridia, abnormal toxicity (general safety test; Ph. Eur.).Manufactured according to EU GMP guidelines.(Clostridiopeptidase A)EC 3.4.24.3 Mr ca. 70 000 - 120 000 (collagenases) CAS [9001-12-1]References and Definitions*Unit definitions:Collagenase: 1 U according to Wnsch (2) catalyzes the hydrolysis of 1 mol 4-phenylazobenzyloxycarbonyl-L-prolyl-L-leucylglycyl-L-prolyl-D-arginine per minute at 25 °C, pH 7.1.**Endotoxin: Ph. Eur. [1 Endotoxin Unit is equal to 1 International Unit of a WHO appoved reference standard endotoxin (RSE)].References:1. Bond, M.D. & van Wart, H.E. (1984) Biochemistry 23, 3077-30912. Wnsch, E. & Heidrich, H.G. (1963) Hoppe-Seyler ́s Z. Physiol. Chem. 333, 149-51. Specification: 3.00 U/mg MDL Number: MFCD00130830 EC Number: 232-582-9 PubChem CID: 44384985 Isomeric SMILES: CCCCCCCC[C@H]1CC[C@@]2([C@@]1(CC[C@]3(C2CC[C@@]4([C@@]3(CC5=C(C4)N=C6C[C@]7([C@@](CCC8[C@@]7(CC[C@]9([C@]8(CC[C@@H]9CCCCCCCC)C)C)C)(CC6=N5)C)C)C)C)C)C)C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C278974-SCI_52932f25f3af4dabb1a82b7fb045a325.pdf

UPC:

41116111

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C278974-2000U

CAS:

2593923

Product Size:

2000U

Hazard Statement Codes:

H334

Precautionary Statement Codes:

P261:P284:P304+P340:P342+P311:P501