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Sigma-Aldrich

COMPLEMENT C6 DEFICIENT SERUM HUMAN

Application Complement C6 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). A deficiency of C6 may result in an increased susceptibility to Neisseria meningitidis .

Description

Application

Complement C6 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). A deficiency of C6 may result in an increased susceptibility to Neisseria meningitidis. Research has identified that a mutation which leads to a 31 bp deletion in exon 10 in the C6 gene results in C6 deficiency. A coagulation defect has also been observed in mice that are C6 deficient.

Physical form

Supplied as a solution in PBS, pH 7.4

Analysis Note

C6 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Specifications
UPC:
41181519
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
ML
MPN:
C1288-1ML
Temperature Control Device:
Yes
Catalog No. C005B-103847
Price: $641.79
List Price: $713.10
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