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MP BIOMEDICALS

Compound 48/80, 50mg

Compound 48/80 is a oligomeric mixture of condensation products from N-methyl-p-methoxyphenethylamine and formaldehyde. It is a mixture of low-molecular weight polymers having a degree of polymerization between 3 to 6.

Description

Compound 48/80 is a oligomeric mixture of condensation products from N-methyl-p-methoxyphenethylamine and formaldehyde. It is a mixture of low-molecular weight polymers having a degree of polymerization between 3 to 6. Protein G activator similar to mastoparan. Calmodulin and platelet PLC inhibitor. Compound 48/80 used to induce degranulation of GnRH-like immunoreactivity of mast cells in the brain and mesentery and for elucidating the mechanism by which anti-allergic medications suppress conjunctivitis. Potent histamine releasing agent, primarily from mast cells, with a subsequent depletion of tissue histamine. It is the action of mast cell mediators on the cardiovascular system that leads to circulatory collapse. The toxicity is due to more than histamine release. It is a potent inhibitor of phospholipase C. Activates G proteins by a mechanism analogous to that of mastorparan. Inhibits calmodulin and human platelet PLC and exhibits a concentration dependent biphasic modulation of human platelet PLA2.

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Specifications
UPC:
51314387
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
0215902650
Model Number:
C825J62
Temperature Control Device:
Yes
Controlled Substances and Cyanide:
Yes
Catalog No. C003B-207872
Price: $575.68
List Price: $639.64
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