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Compound 48/80 (C15-1346-444)

Catalog No.
C15-1346-444
Manufacturer No.
C2313-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GR
Price: $1,133.14
List Price: $1,259.05

Compound 48/80, is the condensation product of N -methyl p -methoxyphenethylamine and formaldehyde. Application Compound 48/80 has been used: to stimulate hemocytes for histamine release for measurement in ELISA and flow cytometry to induce mast

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General description

Compound 48/80, is the condensation product of N-methyl p-methoxyphenethylamine and formaldehyde.

Application

Compound 48/80 has been used:

  • to stimulate hemocytes for histamine release for measurement in ELISA and flow cytometry
  • to induce mast cell degranulation
  • to induce anaphylactic activity, dermatitis, pruritis, inflammation in mice

Biochem/physiol Actions

Compound 48/80 (C 48/80) is a hypotensive agent, which promotes release of histamine. C 48/80 reduces the phagocytic ability of hemocytes in Styela plicata. C 48/80 promotes degranulation of mast cells. It Inhibits calmodulin, phospholipase C, endoplasmic reticulum (ER) Ca2+ ATPase and activates G proteins.

Preparation Note

Condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde.

UPC:
51392227
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
C2313-1G


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