Compound 6877002 (C007B-096166)

Product Application：CD40-TRAF6 signaling inhibitor has been used to treat human embryonic kidney (HEK)-293T cells to test its inhibitory effect on the tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6) leading to subsequent abrogation of (P2RY6)-dependent nuclear factor kappa B (NF-κB). Product Description：TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction, compound VII, shows inhibition of NF-κB activation in RAW cells, extracted from patent WO2014033122A1. TRAF-STOP 6877002 prevents the progression of established atherosclerosis in mice, reduces leukocyte recruitment and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques. Specification: 0.98 Molecular Formula: C17H17NO Molecular Weight: 251.32 PubChem CID: 2291556 Isomeric SMILES: CC1=CC(=C(C=C1)C)N/C=C/C(=O)C2=CC=CC=C2

UPC:

51112525

Condition:

New

Weight:

0.97 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C275134-50mg

CAS:

433249-94-6

Product Size:

50mg