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Aladdin Scientific

Copanlisib dihydrochloride (C007B-578172)

Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.

Description

Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib dihydrochloride has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib dihydrochloride has superior antitumor activity .

Specifictaions: Moligand™, ≥99%

MDL Number: C23H30Cl2N8O4

Molecular Formula: 553.44

Molecular Weight: 815-039-6

PubChem CID: 135565785

Isomeric SMILES: COC1=C(C=CC2=C3NCCN3C(=NC(=O)C4=CN=C(N=C4)N)N=C21)OCCCN5CCOCC5.Cl.Cl

Specifications
UPC:
51172162
Condition:
New
Weight:
1.06 Ounces
HazmatClass:
No
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
C651590-25mg
CAS:
1402152-13-9
Product Size:
25mg
Catalog No. C007B-578172
Price: $584.10
List Price: $648.99
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