Costundide

Costunolide is a sesquiterpene lactone isolated from Magnolia sieboldii. The compound is described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity. Additionally, Costunolide is reported to inhibit the activity of TERT (telomerase). Studies indicate that Costunolide activates JNK downstream of ROS in leukemia cells, and upstream of Bcl-2. The compound has also been suggested to act as an inhibitor of NOS (nitric oxide synthase) and the VEGFR KDR/Flk-1 signaling pathwayA sequiterpene lactone that inhibits telomerase

FPTase and telomerase inhibitor. Apoptotic agent.

Specifications & Purity: Costunolide is a sesquiterpene lactone isolated from Magnolia sieboldii. The compound is described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity. Additionally, Costunolide is reported to inhibit the activity of TERT (telomerase). Studies indicate that Costunolide activates JNK downstream of ROS in leukemia cells, and upstream of Bcl-2. The compound has also been suggested to act as an inhibitor of NOS (nitric oxide synthase) and the VEGFR KDR/Flk-1 signaling pathwayA sequiterpene lactone that inhibits telomerase

Grade: Moligand™

MDL Number: MFCD00210262

Molecular Formula: C15H20O2

Molecular Weight: 232.32

EC Number: 683-148-4

PubChem CID: 5281437

Isomeric SMILES: C/C/1=C\CC/C(=C/[C@@H]2[C@@H](CC1)C(=C)C(=O)O2)/C

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C139779-SCI_d84a4edcc07a09739f180486a66721cd.pdf

UPC:

51392220

Weight:

1.07 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C139779-500mg

Country of Origin:

China

CAS:

553-21-9

Product Size:

500mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H315;H317;H319;H335

Precautionary Statement Codes:

P261;P264;P271;P272;P280;P321;P302+P352;P304+P340;P305+P351+P338;P333+P313;P362+P364;P405;P403+P233;P501;P264+P265;P337+P317;P332+P317;P319