CPI-637 (C007B-102128)

InformationCPI-637 CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 values of 0.03 μM and 0.051μM for CBP and EP300 respectively in TR-FRET assay. It is highly selective against other bromodomains, displaying substantial biochemical activity only against BRD9.TargetsCBP (Cell-free assay); EP300 (Cell-free assay) 0.03 μM; 0.051 μMIn vitroCPI-637 inhibits MYC expression in AMO-1 cells (EC50=0.60 μM).Cell Research(from reference)Cell lines：AMO-1 cells Concentrations：0-5 μM Incubation Time：6 h. Specification: 0.99 Molecular Formula: C22H22N6O Molecular Weight: 386.45 PubChem CID: 121271792 Isomeric SMILES: C[C@@H]1CC(=O)NC2=CC=CC(=C2N1)C3=CC4=C(C=C3)N(N=C4C5=CN(N=C5)C)C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C413937-SCI_4c23599d6b636bd183565b434b6a296a.pdf

UPC:

41115711

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No;ManufacturerName=Aladdin Scientific"

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C413937-10mg

CAS:

1884712-47-3

Product Size:

10mg

Hazard Statement Codes:

H302:H315:H319:H335

Precautionary Statement Codes:

P261:P305+P351+P338

Controlled Substances and Cyanide:

Yes