CTX1 (C007B-342252)

CTX1 is a p53 activator that overcomes HdmX-mediated p53 repression. CTX1 exhibits potent anti-cancer activity in a mouse acute myeloid leukemia (AML) model systemIn VitroCTX1 binds directly to HdmX to prevent p53-HdmX complex formation, resulting in the rapidly induction of p53 in a DNA damage-independent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoCTX1 ( (30 mg/kg; i.p.; five days a week; for 3 weeks) significantly enhances the survival of mice in AML model system . CTX1 exhibited significant anti-cancer activity alone as well as in combination with nutlin-3 . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:p53. Specification: 0.97 Molecular Formula: C14H10N4 Molecular Weight: 234.26 PubChem CID: 435038 Isomeric SMILES: C1=CC2=C(C=C1N)N=C3C=C(C=CC3=C2C#N)N

UPC:

51111610

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C646180-10mg

CAS:

501935-96-2

Product Size:

10mg