Cyclo(-RGDfK) TFA (C007B-102091)

InformationCyclo (-RGDfK) Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.Targetsαvβ3 integrinIn vitroThe constant of affinity (KD) of Cyclo (-RGDfK-) for purified integrin is 41.70 nM. Cyclo (-RGDfK) is reacting with HEK293(β3) cells moderately. Cyclo(-RGDfK-) modified micelles shows strong affinity to T-24 cells and strong inhibitory effect on the proliferation of T-24 cells.In vivoIn athymic mice bearing α(v)β(3)-integrin-positive C6 gliomas, Cyclo (-RGDfK-) modification induces less tumor progression, less tumor metabolic activity, fewer intratumoral vessels.Cell Research(from reference)Cell lines：T-24 cells Incubation Time：72 h. Specification: 0.99 Molecular Formula: C29H42F3N9O9 Molecular Weight: 717.69 PubChem CID: 91759592 Isomeric SMILES: C1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O.C(=O)(C(F)(F)F)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C413847-SCI_f3fd13650405a0032e065e6eae50b79c.pdf

UPC:

51171809

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C413847-5mg

CAS:

500577-51-5

Product Size:

5mg

Hazard Statement Codes:

H302:H315:H319:H335

Precautionary Statement Codes:

P261:P305+P351+P338