CYCLOTRAXIN-B TRIFLUOROACETATE SALT

Catalog No.: C005B-311660
Mfr. No.: SML1769-1MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: MG

Price: $505.08

List Price: $561.20

Biochem/physiol Actions Cyclotraxin-B is a potent and selective Trk B (BDNF/NT-3) receptor inhibitor. Cyclotraxin-B prevents receptor activation by BDNF without interfering with BDNF binding.

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Description
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Biochem/physiol Actions

Cyclotraxin-B is a potent and selective Trk B (BDNF/NT-3) receptor inhibitor. Cyclotraxin-B prevents receptor activation by BDNF without interfering with BDNF binding. Cyclotraxin-B has an IC₅₀ value < 1 nM. In rodent studies Cyclotraxin-B, sometimes fused with tat-protein for increased brain permeability, has been shown to have anxiolytic properties, prevent cold hypersensitivity induced by BDNF, and to reduce cocaine self-administration.

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UPC:: 51152014
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML1769-1MG
CAS:: 1203586-72-4
Temperature Control Device:: Yes

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