CYCLOTRAXIN-B TRIFLUOROACETATE SALT

Biochem/physiol Actions

Cyclotraxin-B is a potent and selective Trk B (BDNF/NT-3) receptor inhibitor. Cyclotraxin-B prevents receptor activation by BDNF without interfering with BDNF binding. Cyclotraxin-B has an IC₅₀ value < 1 nM. In rodent studies Cyclotraxin-B, sometimes fused with tat-protein for increased brain permeability, has been shown to have anxiolytic properties, prevent cold hypersensitivity induced by BDNF, and to reduce cocaine self-administration.

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UPC:

51152014

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

MG

MPN:

SML1769-1MG

CAS:

1203586-72-4

Temperature Control Device:

Yes

Controlled Substances and Cyanide:

Yes