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Sigma-Aldrich

DAPTOMYCIN READY MADE SOLUTION

Biochem/physiol Actions Daptomycin is a natural cyclic lipopeptide antibiotic found in Streptomyces roseosporus . It is has been found to be effective in treating infections caused by aerobic Gram-positive bacteria.

Description

Biochem/physiol Actions

Daptomycin is a natural cyclic lipopeptide antibiotic found in Streptomyces roseosporus. It is has been found to be effective in treating infections caused by aerobic Gram-positive bacteria. Daptomycin inhibits many antibiotic resistant strains such as methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA).

The mode of action of daptomycin is quite different from that of any other antibiotic. Daptomycin binds to bacterial membranes and causes a rapid depolarization of membrane potential. This loss of membrane potential causes inhibition of protein, DNA, and RNA synthesis, which results in bacterial cell death.

Packaging

0.5ML

Preparation Note

The 1 mg/mL solution may be further diluted in an appropriate buffer prior to use. It is recommended that a fresh dilution be made on the day of use.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Shipping Information:

Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.

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Specifications
UPC:
51281609
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
1
Unit of Measurement:
ML
MPN:
SBR00014-0.5ML
CAS:
103060-53-3
Temperature Control Device:
Yes
Catalog No. C005B-315804
Price: $566.94
List Price: $629.94
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