DC_517 (C008B-271095)

DC_517 is a DNA methyltransferase 1 ( DNMT1 ) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively.In VitroDC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively. DC_517 (1.25, 2.5, 5, and 10 μM) potently inhibits the proliferation of HCT116 (human colon cancer) and Capan-1 (human pancreatic adenocarcinoma cells) after treatment for 24, 48, and 72 h. DC_517 (0, 0.75, 1.5, and 3 μM) also dose-dependently induces apoptotic cell death in HCT116 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:DNMT1 0.91 μM (Kd) DNMT1 1.7 μM (IC 50 )

Specifications & Purity: DC_517 is a DNA methyltransferase 1 ( DNMT1 ) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively.In VitroDC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively. DC_517 (1.25, 2.5, 5, and 10 μM) potently inhibits the proliferation of HCT116 (human colon cancer) and Capan-1 (human pancreatic adenocarcinoma cells) after treatment for 24, 48, and 72 h. DC_517 (0, 0.75, 1.5, and 3 μM) also dose-dependently induces apoptotic cell death in HCT116 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:DNMT1 0.91 μM (Kd) DNMT1 1.7 μM (IC 50 )

Grade: Moligand™

Molecular Formula: C33H35N3O2

Molecular Weight: 505.65

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

42203505

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

D646685-1mg

Country of Origin:

China

CAS:

500017-70-9

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90