Deltasonamide 1 (C007B-348872)

Deltasonamide 1 is a PDE6δ-KRas inhibitor. Deltasonamide 1 can inhibit PDE6δ-KRas with a K D of 203 pM. Deltasonamide 1 can be used for the research of tumorsIn VitroDeltasonamide 1 can inhibit PDE6δ-KRas with a K D of 203 pM. Deltasonamide 1 binds to PDE6δ with up to 7 hydrogen bonds, resulting in picomolar affinity. Deltasonamide 1 strongly reduces proliferation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: RTCA of hPDAC cell lines. Concentration: 0.375, 0.75, 1.5, 3, 6, 12 μM. Incubation Time: 60 h. Result: Inhibited proliferation of human pancreatic cancer cell lines.Form:SolidIC50& Target:KD: 203 pM (PDE6δ-KRas). Specification: 0.99 Molecular Formula: C30H39ClN6O4S2 Molecular Weight: 647.25

UPC:

51111746

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

D650925-10mg

CAS:

2088485-33-8

Product Size:

10mg