DEXAMETHASONE-WATER SOLUBLE BIOREAGENT SUITABLE FOR CELL CULTURE

Application

Dexamethasone-Water Soluble has been used as a component of

• Dulbecco′s modified Eagle medium based osteogenic and adipogenic medium for human mesenchymal stem cell culture
• erythroid expansion media for the growth of liver, bone marrow and spleen tissues
• medium 199 (M199) for hepatocyte culture

Biochem/physiol Actions

Dexamethasone is an anti-inflammatory glucocorticoid and a synthetic corticosteroid used for treating corneal inflammation. It inhibits the IL-1β-dependent angiogenesis. Dexamethasone elicits a range of effects on cell survival, cell signaling and gene expression. It favors apoptosis in chondrocytes and impairs development of bone. Dexamethasone is a potential therapeutic agent as it induces apoptosis in multiple myeloma (MM) cells. It elicits its functionality by lowering glucocorticoid receptor (GR) α levels and inhibits colon tumor progression.

Packaging

Package size based on dexamethasone

Other Notes

Contains approx. 65 mg dexamethasone per gram; balance methyl-β-cyclodextrin.

UPC:

51422345

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

100

Unit of Measurement:

MG

MPN:

D2915-100MG

CAS:

50-02-2