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Dexmedetomidine (C007B-136776)

InformationDexmedetomidine is a sedative medication used by intensive care units and anesthetists.In vitroDexmedetomidine has a relatively high ratio of α2/α1-activity (1620:1 as compared with 220:1 for clonidine) and, therefore, is considered a

Description
InformationDexmedetomidine is a sedative medication used by intensive care units and anesthetists.In vitroDexmedetomidine has a relatively high ratio of α2/α1-activity (1620:1 as compared with 220:1 for clonidine) and, therefore, is considered a full agonist of the α2 receptor. This may result in more potent effects of sedation without unwanted cardiovascular effects from α1 receptor activation. The 2-h half-life of dexmedetomidine is nearly 4-fold shorter than that of clonidine, which increases the likelihood that a continuous infusion of dexmedetomidine might be useful for sedation. Dexmedetomidine also has minimum alveolar anesthetic concentration (MAC)-sparing properties, but its use as an anesthetic adjuvant has been complicated by persistent hypotension that has mandated IV fluid administration and vasopressor administration. In addition, its use in large doses is complicated by hypertension from α2 receptor-mediated vascular constriction.In vivoCell Datacell lines:Concentrations:Incubation Time:Powder Purity:≥99%. Specification: 10mM in DMSO Molecular Formula: C13H16N2 Molecular Weight: 200.28
Specifications
UPC:
51361801
Condition:
New
Weight:
0.85 Ounces
HazmatClass:
No;ManufacturerName=Aladdin Scientific"
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
D407960-1ml
CAS:
113775-47-6
Product Size:
1ml
Controlled Substances and Cyanide:
Yes
Catalog No. C007B-136776
Price: $291.20
List Price: $323.56
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