DI-TERT-BUTYL DICARBONATE REAGENTPLUS >=99% (C005B-027088)

Application

Automated Boc protection and deprotection can be done using Synple Automated Synthesis Platform (SYNPLE-SC002), Boc protection cartridges ((SYNPLE-B001), (SYNPLE-B002), and Boc deprotection cartridges (SYNPLE-B011)

Di-tert-butyl dicarbonate (Boc anhydride) can be used:

• As a reagent to introduce Boc protecting group for the amine functionalities.
• To prepare tert-butyl ethers and Boc-alcohols in presence of Lewis acid catalyst.
• As a carboxylating agent for the preparation of a variety of tert-butyl carboxylates.
• For the conversion of amines to corresponding isocyanates, carbamates and urea derivatives.
• As a coupling reagent for anchoring various carboxylic acids to hydroxymethylated resins.
• To synthesize quinolinones and 2-(pseudo)haloquinolines from 2-alkenylanilines in presence of DMAP as a catalyst.

Reagent for the introduction of the Boc protecting group.

Warning

Hydrolyzes to t-butanol and CO₂; causes internal pressure in bottle if exposed to moisture.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

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UPC:

13111000

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

Yes

Quantity:

5

Unit of Measurement:

GR

MPN:

361941-5G

CAS:

24424-99-5

Temperature Control Device:

Yes