Divalent cation ionophore that increases intracellular Ca2+ levels, uncouples oxidative phosphorylation, and inhibits mitochondrial ATPase activity. In mast cells, it induces degranulation and pro-inflammatory cytokine production. (C003B-254965)

Calcimycin is a pyrrole polyether antibiotic that exhibits antibacterial, antifungal, pro-inflammatory, and pro-allergic activities. Calcimycin is a divalent cation ionophore that increases intracellular Ca2+ levels, uncouples oxidative phosphorylation, and inhibits mitochondrial ATPase activity. Calcimycin is especially active against gram positive bacteria. In mast cells, calcimycin activates IKK2 and NF-?B and induces degranulation and pro-inflammatory cytokine production. Grade: ≥98%

UPC:

51111704

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C0246-1 mg

CAS:

52665-69-7