DL-AP5 sodium salt (C007B-130895)

Potent and selective NMDA antagonist; sodium salt of DL-AP5Biological Activity：DL-AP5 Sodium salt is the sodium salt of DL-AP5 (Cat. No. 0105) and a racemic mixture of the D- and L-isomers of AP5, a selective NMDA receptor antagonist that competes with glutamate binding and is commonly used to inhibit NMDA-dependent synaptic plasticity. D-AP5 (Cat. No. 0106) is the more active isomer and displays approximately 52-fold higher potency than the L-isomer, L-AP5 (Cat. No. 0107). In vitro D-AP5 reduces NMDA-induced depolarization of cortical neurons, with no effect on the response to L-Quisqualic acid (Cat. No. 0188) or Kainic acid (Cat. No. 0222). Following spinal injection of D-AP5, NMDA-response is rapidly reduced, with no effect seen on spontaneously active neurons.DL mixture, D-isomer and L-isomer also available. Specification: 0.98 Molecular Formula: C5H11NNaO5P Molecular Weight: 219.11 PubChem CID: 52974251 Isomeric SMILES: C(CC(C(=O)O)N)CP(=O)(O)[O-].[Na+] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D276202-SCI_f3042578b3b149454ad8f82a2893782f.pdf

UPC:

51152302

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

D276202-100mg

CAS:

1303993-72-7

Product Size:

100mg

Precautionary Statement Codes:

P264