DM4-SMe (C007B-348931)

DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs) , which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC 50 of 0.026 nMForm:SolidIC50& Target:Maytansinoids. Specification: ≥98.0% Molecular Formula: C39H56ClN3O10S2 Molecular Weight: 826.46 PubChem CID: 11542407 Isomeric SMILES: C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSC)C)/C)OC)(NC(=O)O2)O

UPC:

12352200

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

D651288-25mg

CAS:

796073-68-2

Product Size:

25mg