Interferon beta-1a

The IFNA2 (interferon alpha 2) gene is mapped to human chromosome 9p21.3.

The interferon &#945 2 (IFN-&#9452) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five &#945 helices.

The interferon &#945 2 (IFN-&#9452) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five &#945 helices.

Interferon &#945 is a cytokine, that belongs to type I interferon (IFNs) family. It possesses 14 genes, including 2 pseudo-genes or allelic forms that encodes for 13 proteins.

Biochem/physiol Actions Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (&#945

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A nonpeptidic thiophenylmethanamine compound that binds interferon-&#945 ( K d = 4 &#181M for human IFN-&#945) and prevents IFN-&#945 and IFNAR interaction-dependent IFN-&#945 production in murine BM-pDCs (bone marrow-derived plasmacytoid

Application Interferon-&#945A human has been used to: study the effect of Chikungunya virus on interferon-mediated JAK (Janus kinase)-STAT (signal transducers and activators of transcription) signaling study the effect of interferon-&#945 and

Application Interferon-&#945A/D human has been used: for identification of coronavirus replicase inhibitors in combination with ACH-806 [1-(4-pentyloxy-3-trifluoromethylphenyl)-3-(pyridine-3-carbonyl)thiourea] to study the effect on hepatitis C

Product Source: cDNA obtained from human fibroblast mRNA expressed in CHO cells. Recombinant Human Interferon Beta 1a (Hu-IFNbeta 1a).

Application Interferon-&#947 from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-&#947-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in

Biochem/physiol Actions I-TAC (Interferon-inducible T-cell &#945 chemoattractant) is a chemokine which participates in recruitment of inflammatory cell. It binds to receptor CXCR3 (C-X-C motif chemokine receptor 3).