(E/Z)-BCI (C007B-155049)

Information(E/Z)-BCI (E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.TargetsROS ; DUSP1 (Cell-free assay); DUSP6 (Cell-free assay) ; 8.0 μM(EC50); 13.3 μM(EC50). Specification: 10mM in DMSO Molecular Formula: C22H23NO Molecular Weight: 317.42 PubChem CID: 5475586 Isomeric SMILES: C1CCC(CC1)NC/2C3=CC=CC=C3C(=O)/C2=C/C4=CC=CC=C4

UPC:

12352200

Condition:

New

Weight:

0.85 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

E421914-1ml

CAS:

15982-84-0

Product Size:

1ml