EGFR/ErbB-2/ErbB-4 inhibitor-2 (C007B-153427)

EGFR/ErbB-2 Inhibitor is a cell-permeable 4-anilino quinazoline compound that acts a potent, reversible, and ATP-competitive inhibitors of EGFR and c-erbB2 (IC|50|= 20 nM & 79 nM, respectively), members of the type I growth factor receptor family that is involved in breast cancer development and progression. Shown to effectively inhibit the proliferation (IC|50|~ 1.2-2.5 μM) of tumor cells overexpressing EGRF or Neu (c-erbB-2). Specification: 0.98 Molecular Formula: C23H21N3O3 Molecular Weight: 387.43 PubChem CID: 9843206 Isomeric SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OCC4=CC=CC=C4)OC Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/E337825-SCI_4b2cc23a030d428f28e9082cd98a1180.pdf

UPC:

51111847

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

E337825-1mg

CAS:

179248-61-4

Product Size:

1mg

Precautionary Statement Codes:

P264