Aladdin Scientific
EN460 (C007B-353582)
EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 ( IC 50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation.In VitroExposure of cells to EN460 or QM295 resulted in the
Description
EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 ( IC 50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation.In VitroExposure of cells to EN460 or QM295 resulted in the accumulation of an ERO1α form with lower mobility, indicative of the reduced state. EN460 and QM295 were also found to activate an unfolded protein response reporter in cultured 293T cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Specification: 10mM in DMSO Molecular Formula: C22H12ClF3N2O4 Molecular Weight: 460.79
Specifications
- UPC:
- 51142511
- Condition:
- New
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- E655310-1ml
- CAS:
- 496807-64-8
- Product Size:
- 1ml
Catalog No.
C007B-353582
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Shipping Lead-Time: 8-12 weeks
