Endogenous calcitonin-RAMP agonist involved in gastric emptying, gastric acid secretion, and enteric contraction. It slows food intake, suppresses gastric acid secretion, and inhibits osteoclast activity. (C003B-256156)

Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic Ÿ-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.

UPC:

51172411

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

A4850-2.5 mg